Dysbiosis : watch out, microbiota in danger

When the microbiota is balanced, it makes it possible to contribute to ensuring good health. In some situations, the microbiota becomes disorganised. This is called dysbiosis.

The source of dysbiosis :

Stress, an unbalanced diet, use of antibiotics or certain anti-inflammatories, the birthing methods and the peri-natal period are factors for the imbalance of the microbiota. Some researchers also add vaccinations to the list.

Various health problems when dysbiosis occurs :

• functional intestinal disturbances (bloating with abdominal pain called colopathy, gastroenteritis or post-antibiotic diarrhoea)

• allergies in young children

• inflammatory intestinal disease (Crohn’s disease)

• fibromyalgia, chronic fatigue syndrome

• and more recently, obesity and diabetes…

Obesity : what if it where the microbiota ?

Studies have made it possible to observe that obese people have a special microbiota profile. Today, studies are concentrating on these famous bifidobacteria, which are not as numerous in obese people.

We also know that flora that is less rich in bifidobacteria has a tendency to save energy and therefore promote weight gain, while flora that is rich in bifidobacteria promote energy consumption and thus weight loss.

Delzenne, N. & Cani, P. (2009) Modulation nutritionnelle de la flore intestinale : une nouvelle approche diététique dans la prise en charge de l’obésité ? [Nutritional modulation of the intestinal flora : a new dietary approach in treatment of obesity ?]
Cah Nutr Diet 44 : 42-46.
Duncan, S. H., Lobley, G. E., Holtrop, G., Ince, J., Johnstone, A. M., Louis, P. & Flint, H. J. (2008) Human colonic microbiota associated with diet, obesity and weight loss. Int J Obes (Lond) 32 : 1720-1724